Category Archives: publications
Suggestions for global coagulation assays for the assessment of COVID-19 associated hypercoagulability
Tom W van de Berg, Anne-Marije M Hulshof, Magdolna Nagy, Rene van Oerle, Jan-Willem Sels, Bas van Bussel, Hugo Ten Cate, Yvonne Henskens, Henri M H Spronk, Dutch Covid-19 and Thrombosis Coalition (DCTC)Thromb Res. 2021 May;201:84-89PMID: 33662799 Introduction: Severe acute … Continue reading
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Tagged COVID-19, fibrinogen, heparin, ROTEM, thrombin generation
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Serial EXTEM, FIBTEM, and tPA Rotational Thromboelastometry Observations in the Maastricht Intensive Care COVID Cohort-Persistence of Hypercoagulability and Hypofibrinolysis Despite Anticoagulation
Anne-Marije Hulshof, Renée A G Brüggemann, Mark M G Mulder, Tom W van de Berg, Jan-Willem E M Sels, Renske H Olie, Bart Spaetgens, Alexander S Streng, Paul Verhezen, Iwan C C van der Horst, Hugo Ten Cate, Henri M … Continue reading
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Tagged COVID-19, fibrinolysis, pulmonary embolism, ROTEM, thromboelastometry, thrombosis
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Design and synthesis of a multivalent catch-and-release assay to measure circulating FXIa
S H E van der Beelen, S M Agten, D P L Suylen, K Wichapong, J Hrdinova, B M E Mees, H M H Spronk, T M HackengThromb Res. 2021 Apr;200:16-22.PMID: 33513452 Background: Decreased blood coagulation factor (F)XIa levels have … Continue reading
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Tagged Catch-and-release system, coagulation, Factor XIa, FXIa, thrombosis
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Thrombin-Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
Anne-Marije Hulshof, H Coenraad Hemker, Henri M H Spronk, Yvonne M C Henskens, Hugo Ten CateInt J Mol Sci. 2021 Mar 4;22(5):2590.PMID: 33806700 Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to … Continue reading
Posted in publications, research
Tagged fibrinogen, immune system, inflammatory disease, thrombin, thrombin generation
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