Category Archives: publications
Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease.
Kremers BMM, Posma JN, Heitmeier S, Glunz J, Ten Cate H, Pallares Robles A, Daemen JHC, Ten Cate-Hoek AJ, Mees BME, Spronk HMH. Sci Rep. 2022 Nov 1;12(1):18388. PMID: 36319844 Peripheral artery disease (PAD) patients have an increased cardiovascular risk … Continue reading
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Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism.
Baidildinova G, Ten Cate V, Nagler M, Panova-Noeva M, Rapp S, Köck T, Prochaska JH, Heitmeier S, Gerdes C, Schwers S, Konstantinides SV, Münzel T, Espinola-Klein C, Lackner KJ, Spronk HMN, Ten Cate H, van der Meijden PEJ, Leineweber K, … Continue reading
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Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort.
an de Berg TW, Mulder MMG, Alnima T, Nagy M, van Oerle R, Beckers EAM, Hackeng TM, Hulshof AM, Sels JEM, Henskens YMC, van der Horst ICC, Ten Cate H, Spronk HMH, van Bussel BCT; MaastrICCht Collaborators. Front Cardiovasc Med. … Continue reading
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Dual pathway inhibition as compared to acetylsalicylic acid monotherapy in relation to endothelial function in peripheral artery disease, a phase IV clinical trial.
Willems LH, Thijssen DHJ, Groh LA, Kooijman NI, Ten Cate H, Spronk HMH, Donders ART, van der Vijver-Coppen RJ, van Hoek F, Nagy M, Reijnen MMPJ, Warlé MC. Front Cardiovasc Med. 2022 Oct 6;9:979819. PMID: 36277757 Objective: Dual pathway inhibition … Continue reading
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Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability.
van Gorp RH, Baaten CCFMJ, Habibi A, Jaminon AMG, Peeters FECM, Leenders P, Crijns HJGMC, Heemskerk JWM, Reutelingsperger CP, Spronk HM, Schurgers LJ. Eur Heart J Open. 2021 Aug 6;1(2):oeab017. PMID: 35919270 Aims: Vascular calcification is a hallmark of atherosclerotic … Continue reading
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EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia.
Bochenek ML, Gogiraju R, Großmann S, Krug J, Orth J, Reyda S, Georgiadis GS, Spronk HM, Konstantinides S, Münzel T, Griffin JH, Wild P, Espinola-Klein C, Ruf W, Schäfer K. JCI Insight. 2022 Jul 22;7(14):e157701. PMID: 35700057 Blood clot formation … Continue reading
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Prevalence and determinants of atrial fibrillation progression in paroxysmal atrial fibrillation.
Nguyen BO, Weberndorfer V, Crijns HJ, Geelhoed B, Ten Cate H, Spronk H, Kroon A, De With R, Al-Jazairi M, Maass AH, Blaauw Y, Tieleman RG, Hemels MEW, Luermans J, de Groot J, Allaart CP, Elvan A, De Melis M, … Continue reading
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Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis.
Pallares Robles A, Ten Cate V, Schulz A, Prochaska JH, Rapp S, Koeck T, Panova-Noeva M, Heitmeier S, Schwers S, Leineweber K, Seyfarth HJ, Opitz CF, Spronk H, Espinola-Klein C, Lackner KJ, Münzel T, Andrade-Navarro MA, Konstantinides SV, Ten Cate … Continue reading
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Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background.
van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Thromb J. 2022 Jun 8;20(1):32. PMID: 35676710 Background: The … Continue reading
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Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity.
Dólleman SC, Agten SM, Spronk HMH, Hackeng TM, Bos MHA, Versteeg HH, van Zonneveld AJ, de Boer HC. J Thromb Haemost. 2022 Apr;20(4):996-1007. PMID: 35037739 Background: Atrial fibrillation (AF) can lead to the loss of microvascular integrity thereby enhancing AF … Continue reading
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