Daily Archives: April 20, 2022

Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity.

Dólleman SC, Agten SM, Spronk HMH, Hackeng TM, Bos MHA, Versteeg HH, van Zonneveld AJ, de Boer HC. J Thromb Haemost. 2022 Apr;20(4):996-1007. PMID: 35037739 Background: Atrial fibrillation (AF) can lead to the loss of microvascular integrity thereby enhancing AF … Continue reading

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